2,408 research outputs found

    The Vortex of Continuous Development of Embedded Systems: An Inquiry into Agility Orchestration

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    Agile methodologies have become a popular and widely accepted method for managing software development. Since the inception of the Agile Manifesto over ten years ago, agile development techniques have superseded waterfall methods in many, if not most, software development organizations. Despite its apparent success, many companies have struggled with the adoption and implementation of agile, and exactly what level of adoption provides optimum agility. Agility is commonly held in the literature to be constructed of elements external to a company or project but may in fact be composed of both external and internal elements. The exact relationship of the adoption of agile development techniques and their relationship to the actual agility of a business remain unclear. A primary contributor to this uncertainty is the somewhat amorphous definition of agile itself. In academic literature, the concept is still relatively young and loosely defined. In practice, organizations have largely opted for a hybrid approach to agile, mixing its concepts and methods with existing Stage Gate or waterfall methodologies. This has made the management of agile even more complex. Crucially, there is no definition or criterion available to determine the appropriate mix of agile and waterfall processes in an embedded software development context nor is there a method to determine the impact of one against the other. These issues beg the question: how do organizations manage agility? This interpretive case study provides an empirical account of how stakeholders manage both market and process agility in an embedded systems context via a hybrid agility implementation and product genesis. As a result, we provide the notion of agile vorticity, as the point at which market and process agility collide to produce business momentum at a specific point of innovation within the agile business vortex

    Lake Michigan Salmonid Stocking Costs in Wisconsin

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    The costs of stocking salmonids in the Wisconsin waters of Lake Michigan are estimated for 1985. Estimation procedures and costs per stocked and captured fish are presented. Fingerlings of a species were found in most cases to cost more per captured fish than yearlings. However chinook salmon fingerlings were least expensive at an average cost of only 0.35percapturedfish.Mostexpensivewerebrookyearlingsandfingerlingsat0.35 per captured fish. Most expensive were brook yearlings and fingerlings at 12.67 and $10.14 respectively. While a full policy evaluation awaits additional research on species specific benefits, three tentative conclusions can be drawn for the Wisconsin fishery. First, the role of brook trout in the fishery should be reviewed. Second, despite difficulties with lake trout rehabilitation, the role of lake trout in the sport fishery is encouraging and may justify continued stocking. Finally, increased stocking of the popular chinook salmon may be justified if the recent problems of low capture-per-release rates can be solved.restocking costs, benefit-cost methodology, sport fisheries, salmonids, Lake Michigan, Environmental Economics and Policy, Resource /Energy Economics and Policy,

    Manipulating graded exercise test variables affects the validity of the lactate threshold and VO2peak

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    Background To determine the validity of the lactate threshold (LT) and maximal oxygen uptake (V_ O2max) determined during graded exercise test (GXT) of different durations and using different LT calculations. Trained male cyclists (n = 17) completed five GXTs of varying stage length (1, 3, 4, 7 and 10 min) to establish the LT, and a series of 30-min constant power bouts to establish the maximal lactate steady state (MLSS). V_ O2 was assessed during each GXT and a subsequent verification exhaustive bout (VEB), and 14 different LTs were calculated from four of the GXTs (3, 4, 7 and 10 min)—yielding a total 56 LTs. Agreement was assessed between the highest V_ O2 measured during each GXT (V_ O2peak) as well as between each LT and MLSS. V_ O2peak and LT data were analysed using mean difference (MD) and intraclass correlation (ICC). Results The V_ O2peak value from GXT1 was 61.0 ± 5.3 mL.kg-1.min-1 and the peak power 420 ± 55 W (mean ± SD). The power at the MLSS was 264 ± 39 W. V_ O2peak from GXT3, 4, 7,10 underestimated V_ O2peak by ~1–5 mL.kg-1.min-1. Many of the traditional LT methods were not valid and a newly developed Modified Dmax method derived from GXT4 provided the most valid estimate of the MLSS (MD = 1.1 W; ICC = 0.96). Conclusion The data highlight how GXT protocol design and data analysis influence the determination of both V_ O2peak and LT. It is also apparent that V_ O2max and LT cannot be determined in a single GXT, even with the inclusion of a VEB

    The Birds of Indonesia, Kukila Checklist No. 1: Additions, corrections and notes - 2

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    This is the second update of the Kukila Checklist of the birds of Indonesia. The authorship of these checklist updates will be the Ornithological Society of Indonesia, or Kukila for ease of reference. The inaugural checklist was published in 1992 (Andrew 1992) and the first update appeared a year later (Andrew 1993). This second supplement is organized in the same way except that the many issues of classification that have been published since 1993 will be desk with in a separate paper that is currently in preparation. The main objective of the present paper is to present new distributional data. Most of the data are derived from published references, although a few are from submitted notes that await publication

    Rotavirus Infection: A Systemic Illness?

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    Candy discusses a new study inPLoS Medicine that challenges the view that in children with rotavirus diarrhea, the virus is confined to the upper small intestine

    Automation of large scale transient protein expression in mammalian cells

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    Traditional mammalian expression systems rely on the time-consuming generation of stable cell lines; this is difficult to accommodate within a modern structural biology pipeline. Transient transfections are a fast, cost-effective solution, but require skilled cell culture scientists, making man-power a limiting factor in a setting where numerous samples are processed in parallel. Here we report a strategy employing a customised CompacT SelecT cell culture robot allowing the large-scale expression of multiple protein constructs in a transient format. Successful protocols have been designed for automated transient transfection of human embryonic kidney (HEK) 293T and 293S GnTI⁻ cells in various flask formats. Protein yields obtained by this method were similar to those produced manually, with the added benefit of reproducibility, regardless of user. Automation of cell maintenance and transient transfection allows the expression of high quality recombinant protein in a completely sterile environment with limited support from a cell culture scientist. The reduction in human input has the added benefit of enabling continuous cell maintenance and protein production, features of particular importance to structural biology laboratories, which typically use large quantities of pure recombinant proteins, and often require rapid characterisation of a series of modified constructs. This automated method for large scale transient transfection is now offered as a Europe-wide service via the P-cube initiative

    Water as a Factor in Energy Resources Development

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    Water, in many cases, is a key factor in the development of energy resources in the western states. The total water supply available in the arid west is fixed; yet potential water uses in the region are growing continually. In fact, in many areas quantities of water desired to be put to beneficial use has already surpassed the limit of local supplies as indicated by filings for water rights. The availability of water, in adequate quantities and of suitable quality, is one of the essentials to the economic viability of some economic sectors in the states in the Colorado River Basin. Many existing water uses are already under economic pressure which could shift water to users who can afford to pay higher prices. With the entire region undergoing an energy boom, Duchesne and Uintah Counties, which are agriculture oriented, for example, may see water bought from agriculture for energy development
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